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. 2014 Feb 3;9(2):e85703. doi: 10.1371/journal.pone.0085703

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© 2014 Axt et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Structure of the 35S pre-rRNA, showing the location of cleavage site A2. (B) Pre-rRNA processing pathways via nascent transcript cleavage (NTC) and released transcript cleavage (RTC). The points at which Rat1 functions as a 5′ exonuclease are indicated.