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. 2014 Feb 3;9(2):e87142. doi: 10.1371/journal.pone.0087142

Table 4. Enrichment analysis of 742 probe set whose expression levels were down-regulated only in the presence of ethanol plus polyphenols.

GO-terms p value
GO:0044087∼regulation of cellular component biogenesis* 1.75E-02
GO:0044267∼cellular protein metabolic process 1.04E-06
 GO:0006464∼protein modification process N/A
 GO:0006457∼protein folding 1.75E-02
  GO:0043687∼post-translational protein modification* 1.05E-02
  GO:0006467∼protein thiol-disulfide exchange* 8.04E-03
 GO:0006412∼translation 1.66E-05
  GO:0006413∼translational initiation* 9.39E-03
GO:0034641∼cellular nitrogen compound metabolic process 3.13E-05
 GO:0044106∼cellular amine metabolic process 5.87E-03
  GO:0006520∼cellular amino acid metabolic process* 1.10E-02
  GO:0048008∼platelet-derived growth factor receptor signaling pathway* 7.09E-03
  GO:0008213∼protein amino acid alkylation 1.81E-02
   GO:0006479∼protein amino acid methylation* 1.81E-02
  GO:0007431∼salivary gland development 2.49E-02
   GO:0007435∼salivary gland morphogenesis* 1.74E-02
 GO:0006461∼protein complex assembly 4.13E-03
  GO:0043623∼cellular protein complex assembly N/A
   GO:0051258∼protein polymerization* 1.33E-02
  GO:0070647∼protein modification by small protein conjugation or removal 7.34E-05
   GO:0032446∼protein modification by small protein conjugation 5.85E-04
    GO:0016567∼protein ubiquitination* 2.89E-03
  GO:0016070∼RNA metabolic process 2.31E-05
   GO:0006396∼RNA processing 3.08E-05
    GO:0008380∼RNA splicing* 5.60E-05
    GO:0006397∼mRNA processing* 4.42E-07
   GO:0045934∼negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.09E-02
    GO:0016481∼negative regulation of transcription* 1.94E-02
    GO:0006829∼zinc ion transport* 8.41E-03
   GO:0019941∼modification-dependent protein catabolic process 5.39E-06
    GO:0006511∼ubiquitin-dependent protein catabolic process 9.87E-08
     GO:0043161∼proteasomal ubiquitin-dependent protein catabolic process* 6.20E-04
   GO:0016568∼chromatin modification 1.15E-03
    GO:0016569∼covalent chromatin modification 2.36E-02
     GO:0016570∼histone modification* 1.86E-02
      GO:0006357∼regulation of transcription from RNA polymerase II promoter* 6.75E-03
*

: Lowest level groupings in which significant enrichment was observed.