Table 5. Summary of the predicted polyphenol's effect on metabolism.
| Metabolic pathways | EtOH vs control | EtOH+EA or RSV vs EtOH | EtOH+EA or RSV vs control |
| TCA cycle | down | up | up |
| Steoid and Bile acid synthesis * | down | up | up |
| β-oxidation * | down | up | up |
| α-oxidation | down | up | up |
| Tetrahydrofolate metabolism | down | up | up |
| Core clock (day) | up | down | down |
| Glycogen synthesis * | down | up | |
| Long chain unsaturated fatty acid synthesis | down | up | |
| Glycolysis | up | down | |
| Pentose phosphate pathway | up | down | |
| Gluconegenesis | up | ||
| NAD synthesis | up | ||
| Methionine metabolism | up | ||
| Urea cycle | up | ||
| Core clock (night) | up | ||
| Clock output regulators | up |
*
: metabolic pathways that include CAR-regulated gene products.