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. 2014 Feb 3;9(2):e87537. doi: 10.1371/journal.pone.0087537

Figure 1. Figure 1. β-catenin mRNA expression was upregulated in lung cancer cell lines following treatment with 5-Aza-CdR.

Figure 1

A: −1,124–11,114 bp revealed the presence of two CpG islands (positions −1,124–876 and 10,676–11,114). B: Treatment of lung cancer cell lines with 5-Aza-CdR resulted in varying levels of increased β-catenin mRNA expression. Statistical analysis by t-test showed increased β-catenin mRNA expression in lung cancer cell lines, which were treated with 5-Aza-CdR, compared to untreated cells (SPC, P = 0.030; H460, P = 0.308; LTE, P = 0.035; A549, P = 0.151).