Table 1. Patient Demographics and Baseline Disease Characteristics (N = 35 patients).

Variable	No. of Patients (%)
Age, years; Median (range)	52 (30–87)
Cutaneous primary	29 (83)
Mucosal primary	5 (14)
Unknown primary	1 (3)
Gender: Female	13 (37)
Gender: Male	22 (63)
Performance status (ECOG): 0	22 (63)
Performance status (ECOG): 1	13 (37)
Recurrent disease after prior surgery	27 (77)
Prior adjuvant HDI*	12 (34)
Presence of in-transit metastases	18 (51)
Estimated risk stage: IIIB	3 (9)
Estimated risk stage: IIIC	30 (86)
Estimated risk stage: IV (non-evaluable for efficacy)	2 (5)
Tumor Mutational Status: BRAFV600	15 (43)
Tumor Mutational Status: NRASQ61	9 (26)
Tumor Mutational Status: NRAS R73	1 (3)
Tumor Mutational Status: Unknown	3 (9)

^*HDI: high dose interferon-α; ECOG: Eastern Cooperative Oncology Group;