Table 1. Description of chemotherapeutic agents and dosages.

Agent	Class	Mechanism of action	Typical cancers	Clinical dose range	Half-life (in vivo)	Macrobead treatment
						Time	Dose
Paclitaxel (Taxol®)	Microtubule inhibitor	Blocks microtubule disassembly	Breast, lung, ovarian	135–175 mg/m2	13–20 h	1 d	0.35 µg/ml
							3.5 µg/ml
							35 µg/ml
Docetaxel (Taxotere®)	Microtubule inhibitor	Blocks microtubule disassembly	Breast, lung, prostate	60–100 mg/m2 over 1 h	12 h	1 d	0.5 µg/ml
							5.0 µg/ml
							50 µg/ml