Table 3. Significantly differently expressed chromatin and DNA modifying enzymes as determined by Human Epigenetic Chromatin Modification Enzyme qPCR Array.

		MDA-MB-231 WA 700 nM/MDA-MB-231 DMSO		MCF-7 WA 700 nM/MCF-7 DMSO
Cofactor group	Gene	Fold change	p-value	Fold change	p-value
DNA methyltransferases	DNMT3B	ns*	ns	−3.13	1.63E-03
Histone acetyltransferases	CDYL	3.41	4.57E-02	ns	ns
	MYST2	4.54	3.22E-02	ns	ns
	NCOA3	7.65	2.33E-02	ns	ns
	ESCO2	ns	ns	−3.79	4.91e-03
Histone methyltransferases	PRMT5	3.06	1.71E-02	ns	ns
	SMYD3	−2.17	9.19E-04	ns	ns
SET domain proteins (Histone methyltransferase activity)	SETD2	2.57	2.59E-02	ns	ns
	SETD3	2.00	2.82E-02	ns	ns
	SETD4	4.52	1.16E-03	ns	ns
	SETDB2	3.60	1.05E-02	ns	ns
	SUV420H1	3.74	2.15E-02	ns	ns
Histone demethyltransferases	JARID1B	2.48	1.57E-02	2.47	1.14E-02
	JMJD2C	6.36	9.15E-03	ns	Ns
	JMJD3	22.34	9.14E-03	ns	Ns
	MBD2	2.02	3.18E-02	ns	Ns
Histone ubiquityn ligases	MYSM1	3.41	8.30E-03	ns	Ns
	UBE2B	3.45	6.60E-03	ns	Ns
	USP16	2.35	3.37E-03	ns	Ns
	USP21	2.47	3.56E-02	ns	Ns
Histone kinases	AURKA	ns	ns	−2.37	9.98E-03
	AURKB	ns	ns	−3.75	4.36E-02
	AURKC	6.78	2.21E-02	4.60	1.71E-02
	RPS6KA3	−2.04	4.00E-02	ns	Ns

^* ns- not significant.