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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Nanomedicine. 2013 Aug 3;10(2):359–369. doi: 10.1016/j.nano.2013.07.014

Figure 2.

Figure 2

(A) Images depicting the DNR loading process. The top row shows a sample of NDs processed without DNR and the bottom row shows ND and DNR at a 5:2 mixing ratio. (i) The first panel shows ND and ND:DNR before any treatment. (ii) The second panel shows ND and ND:DNR after the binding environment has been adjusted to 3 mM of NaOH. (iii) The third panel shows the pelleting of ND and ND-R conjugates after centrifugation. (iv) The fourth panel shows the resuspended solution after supernatant from part (iii) was removed and replaced by an equal volume of water. (B) Graph of the DNR loading efficiency for various binding conditions. The red box indicates the optimal binding condition tested and the conditions used for the rest of the study.