Figure 2.

Effect of C75 treatment on the histological morphology of colon in DSS colitis. (A) Representative images of colon tissues stained with hematoxylin and eosin from sham, vehicle and C75-treated mice at d 8. Original magnification 40×. (B) Histological damage score of the colons as described in Materials and Methods. (C) Western blot analysis of cleaved caspase-3 expression in colon tissues collected at d 8. Expression in the sham group is designated as 1 for comparison. Data are expressed as mean ± SEM (n = 5 per group). *P < 0.05 versus sham; ^#P < 0.05 versus vehicle.