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. 2014 Feb;69(2):134–144. doi: 10.6061/clinics/2014(02)10

Figure 3.

Figure 3

The effects of ethyl-p-methoxycinnamate (EPMC) on proliferation and migration of human umbilical vein endothelial cells (HUVECs). A) Graphical representation of the inhibitory effect of EPMC on the percent of viable HUVEC cells at concentrations of 25, 50, 100, and 200 µg/ml. B) The inhibitory effects of EPMC on cell migration in HUVECs. Images were taken under an inverted phase-contrast microscope at 4× magnification after 0, 6, and 12 hours of incubation. Straight lines show the width of the cell-free zone, whereas the circles represent the sites at which the cells completely filled the gap after migration. C) Graphical representation of the inhibitory effect of EPMC on the migration of endothelial cells. All values are represented as the mean ± SEM (n = 6), and *, **, and *** indicate significant differences of p<0.05, p<0.01, and p<0.001, respectively, compared with the control-treated group.