Table 1.
Demographic, clinical, dietary, and genetic characteristics of normal, MCI and MCD sub-samples.
| Normal (n = 1354) | MCI (n = 27) | MCD (n = 52) | |
|---|---|---|---|
| Females, n (%) | 700 (51.70) | 10 (37.00) | 22 (42.30) |
| Age wave 1, years (SD) | 62.54 (1.53) | 62.37 (1.80) | 62.50 (1.60) |
| Education years (SD) | 14.15 (2.57) | 13.06** (1.91) | 13.08** (2.21) |
| Caucasian, n (%) | 1321 (97.60) | 26 (96.30) | 51 (98.10) |
| MMSE | |||
| At wave 1 (SD) | 29.43 (0.85) | 28.41** (1.22) | 28.63** (1.12) |
| At wave 2 (SD) | 29.41 (0.86) | 28.27** (1.19) | 28.45** (1.24) |
| At wave 3 (SD) | 29.32 (0.97) | 27.81** (1.65) | 27.74 (1.93) |
| BMI kg/m2 (SD) | 26.60 (4.99) | 27.27 (4.97) | 27.64** (6.36) |
| ACTIVITY LEVEL, n (%) | |||
| Low | 663 (49.00) | 12 (44.40) | 29 (55.80) |
| Moderate | 516 (38.10) | 13 (48.10) | 19 (36.50) |
| High | 175 (12.90) | 2 (7.40) | 4 (7.70) |
| Diabetes, n (%) | 72 (5.30) | 6** (22.20) | 10** (18.30) |
| Hypertension, n (%) | 831 (61.90) | 16 (61.50) | 31 (60.80) |
| ALCOHOL, n (%) | |||
| Abstainers | 351 (25.90) | 11 (30.70) | 16 (30.80) |
| Moderate | 917 (67.70) | 16 (59.20) | 40 (69.30) |
| Harmful | 86 (6.40) | 0 (0.00) | 0 (0.00) |
| Caloric intake MJ (SD) | 8.54 (2.27) | 9.13 (2.62) | 8.77 (2.36) |
| Present and past smokers, n (%) | 633 (46.8) | 12 (44.40) | 26 (50.00) |
| APOE*E4 carrier, n (%) | 370 (27.30) | 5 (18.50) | 14 (28.80) |
| DIETARY MINERAL INTAKE PER 10 MJ | |||
| Calcium, g (SD) | 1.21 (0.38) | 1.26 (0.42) | 1.23 (0.37) |
| Iron, mg (SD) | 17.78 (3.96) | 17.39 (4.32) | 17.35 (3.82) |
| Magnesium, mg (SD) | 434 (78) | 422 (82) | 427 (78) |
| Potassium, g (SD) | 4.91 (1.00) | 5.03 (1.08) | 4.89 (1.12) |
Differences between clinical and normal groups: significant at *0.05, **0.01.
MMSE, mini-mental state examination; BMI, body mass index.