Fig. 2.

Arachidonic acid metabolite production in vivo in chick embryo liver and heart. Arachidonic acid metabolites were extracted from livers and hearts of chick embryos treated for 24 hours with TCDD (1 nmol/egg) or solvent (controls) as described in Materials and Methods. Means ± S.E. for arachidonic acid–metabolite levels from liver (A) and from heart (B) are plotted. n = 5 individual livers or hearts for each treatment group. **P ≤ 0.01, ***P ≤ 0.001, and ****P ≤ 0.0001; n.s., not significant.