. 2014 Jan 9;2014:145901. doi: 10.1155/2014/145901

Table 11.

Effect of hexane extract of P. canariensis on hepatic glucose regulation enzyme activities of normal and diabetic mice.

Group	G6Pase	GK activity	Glycogen (mg/g)		HK activity
Group	activity (mU)	(mU)	Liver	Skeletal muscle	(U/mg protein)
Normal control	0.40 ± 0.006	3.38 ± 0.05	19.64 ± 2.45	11.74 ± 4.39	1.69 ± 0.07
SD control	0.71 ± 0.005^a	1.36 ± 0.06^a	9.67 ± 3.12^a	4.89 ± 1.34^a	1.31 ± 0.03^a
MD control	0.69 ± 0.002^a	1.27 ± 0.08^a	10.23 ± 4.35^a	5.27 ± 1.56^a	1.29 ± 0.05^a
SD + AL-H	0.53 ± 0.008^ab	2.8 ± 0.04^ab	^d17.53 ± 5.18^b	^d9.78 ± 1.54^b	^d1.53 ± 0.09^ab
MD + AL-H	0.46 ± 0.007^ab	3.09 ± 0.03^ab	^d18.13 ± 5.80^b	^d10.89 ± 2.41^b	^d1.59 ± 0.05^ab
GB 4 (mg/kg)	0.39 ± 0.004^b	3.11 ± 0.04^b	17.78 ± 2.30^b	11.01 ± 1.96^b	1.60 ± 0.03^ab

Each value represents mean ± SD, (n = 10); ANOVA followed by multiple two-tail “t” test. In each vertical column, mean with different superscripts (a, b) differed from each other. Significant difference of diabetic control from normal control ^a P < 0.001. Significant difference of treated groups from diabetic control ^b P < 0.01, ^c P < 0.05, ^d P < 0.01 when compared with glibenclamide 4 mg/kg treated group.