Table 12.
Parameters | Normal C | SD C | MD C | SD + AL-H | MD + AL-H | SD + GB |
---|---|---|---|---|---|---|
SOD—liver | 7.54 ± 2.19 | 3.79 ± 0.82a | 4.05 ± 1.38b | 5.87 ± 0.89b | 6.01 ± 1.05b | 6.80 ± 0.41c |
SOD—kidney | 13.82 ± 3.51 | 7.35 ± 1.37a | 8.36 ± 2.53b | 10.24 ± 2.63b | 11.47 ± 3.41b | 13.025 ± 1.57b |
SOD—pancreas | 54.52 ± 5.21 | 36.47 ± 3.28a | 35.99 ± 5.42b | 43.88 ± 5.39b | 46.90 ± 5.48b | 50.71 ± 4.36b |
CAT—liver | 82.36 ± 6.17 | 44.53 ± 3.13a | 47.32 ± 7.14b | 64.56 ± 6.38b | 67.12 ± 6.74b | 70.26 ± 2.16b |
CAT—kidney | 35.61 ± 2.33 | 20.76 ± 1.65a | 22.01 ± 9.53c | 29.56 ± 2.81c | 32.07 ± 2.53c | 34.17 ± 1.79b |
CAT—pancreas | 59.32 ± 5.38 | 25.56 ± 4.19a | 23.19 ± 5.46a | 40.24 ± 3.67a | 43.79 ± 5.18a | 47.83 ± 4.36c |
GSH—liver | 47.68 ± 7.12 | 21.80 ± 1.97a | 29.15 ± 6.36b | 36.52 ± 4.86b | 39.48 ± 4.36b | 42.38 ± 2.28b |
GSH—kidney | 24.45 ± 3.71 | 5.79 ± 2.06a | 7.21 ± 3.53b | 15.29 ± 3.83b | 17.20 ± 3.53b | 19.27 ± 3.58b |
GSH—pancreas | 12.48 ± 3.39 | 5.19 ± 0.94a | 7.42 ± 2.56b | 6.91 ± 1.80b | 8.47 ± 1.56b | 10.79 ± 1.92b |
GPx—liver | 7.26 ± 1.59 | 4.31 ± 1.30a | 5.39 ± 2.01b | 5.35 ± 1.83b | 5.64 ± 1.87b | 5.92 ± 1.26b |
GPx—kidney | 5.92 ± 1.42 | 3.53 ± 0.92a | 3.40 ± 1.43b | 4.53 ± 1.34b | 4.60 ± 1.73b | 4.78 ± 0.94b |
GPx—pancreas | 4.64 ± 1.19 | 2.32 ± 0.36a | 3.42 ± 1.26b | 3.31 ± 0.61b | 3.70 ± 1.26b | 3.89 ± 0.27b |
All values are expressed as mean ± SEM, n = 6 values. a P < 0.01 when compared to normal control group; b P < 0.01, c P < 0.05 compared to diabetic control group, where the significance was performed by Oneway ANOVA followed by post hoc Dunnett's test. Glibenclamide (GB). Control (C); the values are given in U/mg of protein.