Table 4.
Group | NC | OC | OC + AL-H | OC + AL-C | OC + AL-M |
---|---|---|---|---|---|
Serum plasma | |||||
Total cholesterol (mg/dL) | 70.3 ± 1.3 | 120.5 ± 5.4 | 74.0 ± 3.2a | 71.4 ± 4.2a | 72.6 ± 2.5a |
HDL (mg/dL) | 43 ± 2.0 | 32.0 ± 1.6 | 39.7 ± 2.2a | 40.7 ± 3.2a | 38.9 ± 0.6a |
Triglycerides (mg/dL) | 82.4 ± 3.1 | 115.8 ± 5.3 | 86.2 ± 6.7a | 84.5 ± 5.8a | 87.3 ± 2.0a |
MDA (nmol MDA/mg protein) | 0.05 ± 0.00 | 0.08 ± 0.00 | 0.06 ± 0.00a | 0.05 ± 0.00a | 0.06 ± 0.00a |
Hepatic lipids | |||||
Cholesterol (µmol/g liver) | 18.2 ± 4.3 | 35.6 ± 5.3 | 26.7 ± 6.1a | 25.2 ± 7.5a | 27.0 ± 7.7a |
Triglyceride (µmol/g liver) | 13.8 ± 3.4 | 26.9 ± 4.8 | 17.4 ± 3.3a | 16.8 ± 5.2a | 18.0 ± 5.0a |
Hepatic enzymes | |||||
ALP (U/mL) | 0.52 ± 0.07 | 0.63 ± 0.04 | 0.57 ± 0.04 | 0.54 ± 0.08 | 0.59 ± 0.01 |
SGOT (U/mL) | 1.79 ± 0.08 | 2.01 ± 0.05 | 1.86 ± 0.03 | 1.84 ± 0.05 | 10.88 ± 0.02 |
SGPT (U/mL) | 0.58 ± 0.06 | 0.72 ± 0.02 | 0.65 ± 0.02 | 0.64 ± 0.08 | 0.68 ± 0.06 |
Each value represents mean ± S.E.M. (n = 10 animals in each group) a P < 0.05 versus obese control. Hexane extract (AL-H), chloroform extract (AL-C), and methanol extract (AL-M) from P. canariensis.