Table 6.
Effect of hexane extract of P. canariensis on some serum biochemical parameters of normal and diabetic mice.
| Group | IU/I | g/dL | ||
|---|---|---|---|---|
| SGOT | SGPT | ALP | Total protein | |
| Nondiabetic control | 20.9 ± 3.2 | 24.3 ± 5.8 | 170.3 ± 10.4 | 7.9 ± 2.1 |
| SD control | 39.2 ± 8.9a | 42.3 ± 7.1a | 245.1 ± 11.6a | 4.3 ± 1.5a |
| MD control | 38.7 ± 7.7a | 42.9 ± 8.6a | 239.8 ± 9.7a | 4.0 ± 1.2a |
| SD + AL-H | 27.3 ± 6.2b | 34.6 ± 5.5b | 209.2 ± 10.7b | 6.5 ± 1.4b |
| MD +AL-H | 24.0 ± 4.8b | 28.6 ± 6.3b | 195.8 ± 9.1b | 6.7 ± 2.4b |
| SD + GB | 23.1 ± 8.0b | 25.1 ± 5.7b | 192.1 ± 11.8b | 7.2 ± 3.8b |
Values are expressed as mean ± SEM (n = 6) a P < 0.001 compared with normal control and b P < 0.001 compared with STZ control group. ALP: alkaline phosphatase; SGOT: serum glutamate oxaloacetate transaminase; SGPT: serum glutamate; GB: glibenclamide.