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. Author manuscript; available in PMC: 2014 Oct 24.
Published in final edited form as: Nature. 2013 Oct 13;502(7472):563–566. doi: 10.1038/nature12653

Extended Data Figure 4. Mx2 is required for the full antiviral activity of IFNα in HOS cells.

Extended Data Figure 4

a, Western blot analysis of Mx2 expression HOS cells transduced with vectors expressing control or Mx2-targeted shRNAs, and treated with IFNα. Numbers below each lane indicate fluorescence intensity associated with the Mx2 band. d, Infectious titer of an HIV-1 GFP reporter virus determined using the shRNA containing HOS cells from a, with or without IFNα treatment. Titers are mean+SD, n=3 technical replicates, representative of three experiments.