Table 1.
Changes in ECG parameters.
| Cont | Dox | Adr | Pre BVT | |
|---|---|---|---|---|
| RR | 213.8 ± 13.5 | 188.8 ± 10.0* | 188.1 ± 17.3* | 166.0 ± 10.7** |
| QT | 85.0 ± 10.2 | 84.9 ± 7.8 | 89.1 ± 7.5 | 94.4 ± 10.6 |
| QTc | 141.8 ± 16.6 | 148.0 ± 13.0 | 155.5 ± 11.6 | 172.1 ± 20.1* |
| JT | 64.0 ± 11.3 | 63.5 ± 8.5 | 67.4 ± 9.5 | 72.0 ± 10.6 |
| JTc | 106.4 ± 18.7 | 110.6 ± 14.4 | 117.6 ± 14.9 | 131.3 ± 19.7* |
| JTp | 7.1 ± 2.9 | 10.1 ± 2.8 | 11.8 ± 3.9* | 22.2 ± 4.6** |
| JTpc | 11.8 ± 4.8 | 17.5 ± 4.8 | 20.6 ± 7.1* | 40.5 ± 8.4** |
| Tp-e | 56.9 ± 10.1 | 53.4 ± 7.9 | 55.6 ± 9.4 | 49.8 ± 7.1 |
| Tp-ec | 95.0 ± 16.1 | 93.1 ± 13.5 | 97.0 ± 14.7 | 90.8 ± 13.4 |
Values are shown as the mean (ms) ± SD. *P < 0.05 (compared with control); **P < 0.05 (compared with all others) n = 13.
Cont: control, Dox: doxapram hydrochloride, Adr: adrenaline, and pre BVT: just before the ventricular tachycardia (calculated from the narrow QRS complex). Tp-e: T peak to T end interval, Tp-ec: corrected Tp-e interval.