Fig. 2.

Cell-specific cardiac enhancer classifiers perform with high specificity and sensitivity. (A) Average receiver operating characteristic curves and standard deviations for tenfold cross-validation performed for both motif-alone and motif+ChIP classifiers in 20 independent runs. (B) Enrichment in validated heart, CC and PC genes in the neighborhood of putative cardiac enhancers at different ranks for the motif-alone and motif+ChIP classifiers. Each of these genes is generally associated with only one prediction. Double asterisks indicate significant differences (P<0.005).