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. 2014 Jan 25;4(1):e004188. doi: 10.1136/bmjopen-2013-004188

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions

This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 3.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/3.0/

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Flow diagram for the systematic review of predictive biomarkers in the European Medicines Agency licensing. B-I-D, biomarker–indication–drug; ICD, International Classification of Diseases.