Table 3.
Relative risk (RR) and 95% Confidence Intervals (CI) of reporting poor health status among sarcoma survivors by local control and primary cancer therapy$
Poor General Health1 | Poor Mental Health2 | Functional Impairment1 | Activity Limitation1 | Pain3 | Anxiety4 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
% | RR | 95% CI | % | RR | 95% CI | % | RR | 95% CI | % | RR | 95% CI | % | RR | 95% CI | % | RR | 95% CI | |
Limb Surgery | ||||||||||||||||||
None | 15.1 | 1.00 | 18.6 | 1.00 | ||||||||||||||
AKA* | 23.6 | 1.56 | 1.26–1.94 | 29.8 | 1.45 | 1.21–1.73 | ||||||||||||
BKA** | 24.1 | 1.61 | 1.09–2.36 | 18.8 | 0.95 | 0.63–1.42 | ||||||||||||
U/E Amputation*** | 25.3 | 1.85 | 1.17–2.92 | 12.4 | 0.95 | 0.53–1.72 | ||||||||||||
Limb sparing | 12.6 | 0.92 | 0.69–1.23 | 16.1 | 0.95 | 0.75–1.2 | ||||||||||||
| ||||||||||||||||||
Alkylating Agent | ||||||||||||||||||
None | 10.3 | 1.00 | 14.7 | 1.00 | ||||||||||||||
Any | 12.6 | 1.23 | 0.98–1.55 | 19.9 | 1.51 | 1.26–1.81 | ||||||||||||
| ||||||||||||||||||
Platinum | ||||||||||||||||||
None | 21.0 | 1.00 | ||||||||||||||||
Any | 24.0 | 1.10 | 0.91–1.33 | |||||||||||||||
| ||||||||||||||||||
Vincristine | ||||||||||||||||||
None | 5.4 | 1.00 | ||||||||||||||||
Any | 7.0 | 0.70 | 0.48–0.97 | |||||||||||||||
Abdominal Radiation | ||||||||||||||||||
None | 16.0 | 1.00 | 18.2 | 1.00 | 21.7 | 1.00 | 6.2 | 1.00 | 3.0 | 1.00 | ||||||||
Any | 34.8 | 2.24 | 1.25–4.02 | 26.9 | 1.83 | 1.01–3.33 | 34.6 | 2.28 | 1.5–3.45 | 20.8 | 4.63 | 1.66–12.94 | 12.5 | 4.17 | 1.42–12.26 | |||
| ||||||||||||||||||
Limb Radiation | ||||||||||||||||||
None | 11.4 | 1.00 | 2.7 | 1.00 | ||||||||||||||
Any | 13.6 | 1.19 | 0.91–1.55 | 4.6 | 1.68 | 1.04–2.7 | ||||||||||||
| ||||||||||||||||||
Thoractomy | ||||||||||||||||||
None | 15.7 | 1.00 | ||||||||||||||||
Any | 11.3 | 1.49 | 1.10–2.02 |
Backward selection methods used for model covariate selection and those with p<0.1 were included.
Model adjusted for all variables shown and for tumor location, age at questionnaire, gender
Model adjusted for all variables with RR shown and for tumor location, age at diagnosis
Model adjusted for all variables with RR shown and for tumor location, age at diagnosis, gender
Model adjusted for all variables with RR shown and for tumor location and gender
AKA=Above knee amputation
BKA=Below knee amputation
U/E=Upper Extremity