Table 1.
Patient no./sex/age (years) | Race/ethnic groupa |
ESRD cause | No. of previous transplants |
KPD donor age (years) |
HLA mismatchb |
Blood group |
cPRA%c | Dialysis time d (months) |
KPD wait-time e (months) |
---|---|---|---|---|---|---|---|---|---|
DSA(+) KPD (n=12) | |||||||||
1/F/49 | Black | Lupus | 0 | 56 | 4/6 | O+ | 97 | 74 | 5.5 |
2/M/57 | White | Diabetes | 1 | 56 | 4/6 | B+ | 100 | 22 | 6 |
3/M/66 | White | FSGS | 1 | 44 | 6/6 | A+ | 68 | 54 | 14 |
4/M/38 | White | FSGS | 1 | 48 | 5/6 | B+ | 100 | 73 | 3.5 |
5/F/62 | White | PCKD | 0 | 41 | 5/6 | A+ | 99 | 94 | 6 |
6/F/67 | White | IgA | 0 | 60 | 6/6 | O+ | 63 | 29 | 11 |
7/F/69 | White | FSGS | 0 | 50 | 6/6 | O+ | 99 | 12 | 15 |
8/F/66 | White | PCKD | 0 | 42 | 5/6 | O+ | 69 | 0 | 4.5 |
9/F/51 | Hispanic | PCKD | 0 | 60 | 3/6 | O+ | 98 | 32 | 7 |
10/F/28 | Hispanic | HTN | 0 | 42 | 5/6 | O+ | 27 | 0 | 2 |
11/F/44 | White | HTN | 0 | 47 | 4/6 | O− | 89 | 4 | 5 |
12/F/68 | Asian | HTN | 0 | 43 | 4/6 | B+ | 99 | 37 | 3 |
DSA(−)KPD (n=10) | |||||||||
13/F/52 | Asian | Lupus | 0 | 44 | 2/6 | A+ | 92 | 18 | 2 |
14/F/42 | Black | HTN | 0 | 31 | 3/6 | O− | 76 | 60 | 5 |
15/M/45 | Asian | IgA | 0 | 55 | 6/6 | AB+ | 27 | 42 | To wait-listf |
16/F/43 | White | HTN | 0 | 56 | 4/6 | AB+ | 88 | 65 | To wait-listf |
17/M/43 | Asian | Diabetes | 1 | 60 | 6/6 | O+ | 87 | 23 | 7 |
18/F/38 | Asian | Diabetes | 0 | 37 | 3/6 | A+ | 98 | 39 | 15 |
19/F/47 | White | FSGS | 0 | 46 | 5/6 | B+ | 65 | 14 | 6 |
20/F/46 | Other | MGN | 0 | 64 | 3/6 | AB− | 75 | 45 | To wait-listf |
21/M/34 | Asian | HTN | 1 | 56 | 3/6 | O+ | 98 | 38 | 2 |
22/F/57 | Hispanic | Diabetes | 0 | 49 | 4/6 | O+ | 82 | 81 | 3 |
Abbreviations: cPRA, calculated panel reactive antibody; DSA, donor-specific antibody; ESRD, end-stage renal disease; F, female; FSGS, focal segmental glomerulosclerosis; HLA, human leukocyte antigen; HTN, hypertension; IgA, immunoglobulin A; KPD, kidney paired donation; M, male; MGN, membranous glomerulonephritis; PCKD, polycystic kidney disease.
Patient race/ethnic group is self-reported.
HLA mismatch based on HLA-A, B, and DR loci.
cPRA based on unacceptable antigens using the UNOS calculator (http://optn.transplant.hrsa.gov/resources/allocationcalculators.asp?index=78).
Dialysis time for repeat-transplant patients is measured from time of renal transplant failure to transplant date. Patients with `0' dialysis time were transplanted preemptively.
KPD wait-time is measured from recipient list-date in to the National Kidney Registry matching database to the actual date of transplantation.
Patient without willing living donor who received living-donor renal transplant from KPD pool while on deceased-donor waiting list.