Table 4.
| Imnnunologic benefit derived from DSA(+)KPD
| Intended donor | Matched DSA(+)KPD donor | P-value | |
|---|---|---|---|
| Flow cytometric crossmatch (MCS) | |||
| T-cell, median (range) | 78 (17–19) | 32 (2–161) | <0.003 |
| B-cell, median (range) | 334 (36–12) | 115 (14–222) | <0.008 |
| Single-antigen bead (summed MFI) a | |||
| Class I, median (range) | 0 (0–14,575) | 604 (0–6123) | 0.18 |
| Class II, median (range) | 12,808 (0–37,056) | 3462 (0–11,667) | <0.02 |
| Class I + II median (range) | 16,098 (5522–48,756) | 4291 (1209–11,667) | <0.003 |
Abbreviations: DSA, donor-specific antibody; KPD, kidney paired donation; MCS, median channel shift; MFI, median fluorescence intensity.
a
Values represent the summed MFI values for all DSA found on single-antigen testing for each individual patient.