Table 1.

Available Studies Related to Use of Neural Stem Cell in MS

Authors	Country	Neural Stem cell	Model	Findings
Heffernan et al., 2012	Australia	glial cells	Human	new therapeutic strategy for the treatment of as MS(101)
Payne et al., 2012	Australia	46C-NS cells	Mouse	Improving the efficiency at which NSCs home to inflammatory sites may enhance their therapeutic potential in MS(102)
Song et al., 2012	Australia	induced pluripotent stem (iPS) cells	Human	A novel approach for the study of MS pathophysiology and potential drug discovery(103)
Rasmussen et al., 2011	USA	Sub-ventricular zone cells	Mouse	treatments targeting chronic microglial activation have the potential for enhancing repair in MS(104)
Huang et al., 2011	UK	oligodendrocyte precursor cells (OPCs)	Human	might be useful pharmacological targets to overcoming remyelination failure in MS(105)
Giannakopoulou et al., 2011	Greece	neural precursor cell (NPC)	Mouse	NPC intraventricular transplantation should be accountable for their therapeutic effect in MS(106)
Carbajal et al., 2011	USA	oligodendrocyteprogentior cells (OPCs)	Mouse	highlight the importance of the CXCL12:CXCR4 pathway in regulating homing of engrafted stem cells to sites of tissue damage in the MS(107)
Yip et al., 2003	USA	oligodendrocyteprogentior cells (OPCs)	Human	Emerging knowledge of the molecules that may be involved in such responses may help in the design of future stem cell-based treatment of demyelinating diseases such as multiple sclerosis(108)