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. Author manuscript; available in PMC: 2014 Feb 4.
Published in final edited form as: Cell Mol Bioeng. 2012 Aug 9;5(4):390–401. doi: 10.1007/s12195-012-0243-x

Figure 1. rhIL-2 formulated in 680mM pH7.4 CDHP and 680mM NaDHP remains structurally intact when heated.

Figure 1

Sandwich ELISA measurements of rhIL-2 concentrations formulated in (A) 680mM ChCl pH7.4, (B) 680mM NaCl pH7.4, (C) 680mM NaDHP pH7.4, and (D) 680mM CDHP pH 7.4 versus no CDHP control (white bars), and heated at temperatures ranging from 45°C to 85°C. Data are expressed as mean relative rhIL-2 concentrations ±SEM, normalized to the initial amount (T0) of protein. n=9; *: p<0.05; **: P<0.01.