Table 1.
Baseline patient characteristics
| Patient Characteristics | Total Cohort (N=714) | Inflammation Cohort(n=405)a |
|---|---|---|
| Patient characteristics | ||
| Age (yr) | 64.1±13.7 | 63.7±13.9 |
| Men | 445 (62) | 252 (62) |
| Region | ||
| The Netherlands | 597 (84) | 390 (96) |
| Norway | 15 (2) | 15 (4) |
| Canada | 102 (14) | NA |
| History of cardiovascular disease | 313 (44) | 177 (44) |
| Diabetes mellitus | 170 (24) | 85 (21) |
| Dialysis vintage (yr) | 2 (1–4) | 1.8 (0.9–3.4) |
| Systolic BP (mmHg), predialysis | 147±21 | 142±18 |
| Diastolic BP (mmHg), predialysis | 75±12 | 73±11 |
| Body weight (kg), postdialysis | 72.4±14.4 | 71.7±14.6 |
| Body mass index (kg/m2), postdialysis | 25.4±14.4 | 25.0±4.8 |
| Subjective global assessment classification | ||
| Well nourished | 580 (81) | 345 (81) |
| Mild-to-moderate malnutrition | 123 (17) | 71 (18) |
| Severe malnutrition | 1 (0) | 1 (0) |
| Residual kidney function (defined as urine output>100 ml/24 h) | 376 (53) | 230 (57) |
| Estimated GFR (ml/min per 1.73 m2) | 3.2 (1.3–5.5) | 2.6 (1.2–5.1) |
| Treatment characteristics | ||
| Treatment frequency | ||
| 3×/wk | 668 (94) | 375 (93) |
| 2×/wk | 44 (6) | 30 (7) |
| Duration of a dialysis session (min) | 226±23 | 227±23 |
| Blood flow (ml/min) | 300 (300–348) | 300 (300–325) |
| Dialysis access | ||
| Fistula | 567 (80) | 339 (84) |
| Graft | 100 (14) | 53 (13) |
| Central venous catheter | 47 (6) | 10 (3) |
| Single pool Kt/Vurea | 1.40±0.22 | 1.39±0.20 |
| Laboratory parameters | ||
| Hemoglobin (g/dl) | 11.8±1.25 | 11.9±1.25 |
| Phosphorus (mg/dl) | 5.08±1.53 | 5.16±1.59 |
| Albumin (g/dl)b | 4.0±0.38 | 4.0±0.41 |
| Creatinine (mg/dl), predialysis | 9.74±2.89 | 9.80±2.83 |
| Cholesterol (mg/dl) | 142±37 | 142±39 |
| High-sensitivity C-reactive protein (mg/L) | NA | 3.93 (1.38–10.40) |
| IL-6 (pg/ml) | NA | 2.06 (1.21–3.82) |
Data are presented as the mean±SD, n (%), or median (interquartile range). To convert albumin in g/dl to g/L, multiply by 10. NA, not applicable.
a
Subpopulation of the 714 patients in which CRP and IL-6 measurements were done.
b
Albumin concentrations measured with the bromcresol purple method were converted to bromcresol green concentrations.