Table 3.

Annual rate of change in BMI (kg/m²) in various clinical strata

Stratum	Estimate Slopea	95% Confidence Interval	P Value Slope	P Value Interaction Term
Age<66.8 yr	0.03	−0.08 to 0.13	0.59	Age×time
Age≥66.8 yr	−0.35	−0.47 to −0.23	<0.001	<0.001
Men	−0.20	−0.30 to −0.11	<0.001	Sex×time
Women	−0.07	−0.21 to 0.07	0.30	0.11
DM	−0.24	−0.43 to −0.06	0.01	DM×time
No DM	−0.12	−0.21 to −0.04	0.004	0.21
CVD	−0.31	−0.43 to −0.19	<0.001	CVD×time
No CVD	−0.04	−0.14 to 0.07	0.48	<0.001
RKF	−0.22	−0.33 to −0.12	0.23	RKF×time
No RKF	−0.07	−0.19 to 0.05	<0.001	0.07
Vintage below median	−0.09	−0.20 to 0.03	0.14	Vintage×time
Vintage at and above median	−0.23	−0.34 to −0.12	<0.001	0.60

All analyses on strata were adjusted for age, sex, dialysis vintage and randomized group (excluding the conventional risk factor of the stratum under study), and presence of DM, CVD, and RKF. Estimates in this table may differ slightly from estimates in the text of the Results, because estimates in this table are derived from models performed in the subgroups separately. BMI, body mass index.

^aEstimate slope indicates mean longitudinal change per year in BMI associated with the presence or absence of the conventional risk factor.