Table 3.
Mineral metabolism in glomerular and nonglomerular disease
| Characteristic | Glomerular | Nonglomerular | P Value |
|---|---|---|---|
| Number | 94 | 370 | |
| Age, yr | 15 [13, 16] | 11 [8, 14] | <0.001a |
| GFR, ml/min per 1.73 m2 | 47 [32, 63] | 44 [33, 56] | 0.31a |
| Serum calcium, mg/dl | 9.3±0.4 | 9.4±0.4 | 0.07 |
| Serum phosphorus, mg/dl | 4.4±1.0 | 4.6±0.8 | 0.02a |
| Serum phosphorus z score, SD | 0.13±1.9 | 0.08±1.4 | 0.89 |
| Serum iPTH, pg/ml | 49 [29, 114] | 52 [30, 82] | 0.98a |
| Plasma FGF23, RU/ml | 165 [95, 271] | 131 [90, 194] | 0.01a |
| Serum 25OHD,b ng/ml | 19±12 | 29±11 | <0.001 |
| Serum 1,25(OH)2D,b pg/ml | 26±12 | 31±11 | <0.001 |
| Serum albumin, g/dl | 4.0±0.7 | 4.4±0.3 | <0.001 |
| Urine FEPi, % | 15.4 [10.7, 23.0] | 16.9 [12.2, 23.3] | 0.23a |
| Urine protein to creatinine ratio, mg/mg | 0.95 [0.35, 2.61] | 0.32 [0.14, 0.85] | <0.001a |
Data are means±SD or medians [25th, 75th percentiles]. Mean (median) values were compared using t tests. FEPi calculated as (urine phosphorus×serum creatinine/urine creatinine×serum phosphorus)×100.
a
Mean (median) values were compared using Wilcoxon rank sum tests.
b
25OHD and 1,25(OH)2D were measured in 83 participants with glomerular disease and 293 patients with nonglomerular disease.