Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibition of GRK phosphorylation of tubulin and rhodopsin by paroxetine and CCG-206584
Errors represent the S.E.M. from n experiments performed in duplicate.
| Paroxetine |
CCG-206584 |
||||
|---|---|---|---|---|---|
| plogIC50 ± S.E.M. | n | plogIC50 ± S.E.M. | n | ||
| Tubulin | GRK1 | 3.8 ± 0.04 | 7 | 3.8 ± 0.06 | 5 |
| GRK2 | 5.6 ± 0.04 | 9 | 5.6 ± 0.03 | 7 | |
| GRK5 | 3.9 ± 0.05 | 4 | 4.0 ± 0.06 | 6 | |
| Rhodopsin | GRK1 | 3.5 ± 0.07a | 3.7 ± 0.4 | 3 | |
| GRK2 | 4.7 ± 0.04a | 5.2 ± 0.04 | 5 | ||
| GRK5 | 3.6 ± 0.03a | 4.1 ± 0.07 | 4 | ||
From Thal et al., 2012.
