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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Biomaterials. 2014 Jan 3;35(9):2752–2759. doi: 10.1016/j.biomaterials.2013.12.039

Figure 4. MSC sheets enhance devitalized allograft osteointegration with host bone, and induces extensive bone callus formation spanning the allograft at 4- and 6-weeks post-surgery.

Figure 4

Representative microCT volumetric rendering of the grafted femurs with direct seeding of MSCs (B, E, H, K) and MSC sheets (C, F, I, L) at 4- and 6-weeks post-surgery. Allograft alone was used as the control (A, D, G, J). Quantification of bone volume/total tissue volume (BV/TV) from the mineralized calluses of each group (M). (*, p < 0.05 compared with allograft alone; #, p<0.05 compared with allograft + MSC).