. Author manuscript; available in PMC: 2014 Jul 1.

Published in final edited form as: Ann Surg Oncol. 2013 Jan 20;20(7):2364–2372. doi: 10.1245/s10434-012-2834-0

TABLE 4.

Metastatic ULMS—univariable and multivariable analysis for disease-specific survival

Patient/tumor variables^a	N	Univariable			Multivariable
Patient/tumor variables^a	N	Hazard ratio	95 % CI	p value	Hazard ratio	95 % CI	p value
Race (white vs. other)	149/43	0.59	0.39–0.90	0.0136^b	0.75	0.48–1.19	0.2254
Synchronous intra-abdominal tumor (yes vs. no)	104/88	1.59	1.11–2.26	0.0105^b	1.34	0.92–1.96	0.1320
Pulmonary metastasis	164	2.32	1.28–4.23	0.0058^b	2.56	1.16–5.62	0.0194^b
Tumor burden (multiple sites vs. single sites of metastases)	38/154	1.92	1.26–2.92	0.0022^b	1.18	0.75–1.89	0.4833
Multiple metastatic lesions within 1 organ vs. single lesion	192	1.67	1.05–2.65	0.0300^b	0.79	0.44–1.42	0.4332
Chemotherapy (yes vs. no)	173/13	2.91	1.18–7.14	0.0200^b	1.29	0.49–3.40	0.6100
Surgery with curative intent (yes vs. no)	90/92	0.23	0.15–0.34	<0.0001^b	0.25	0.16–0.39	<0.0001^b

CI confidence interval

Age, previous hormone replacement therapy, time from primary diagnosis to development of metastases, and extrapulmonary metastases were analyzed and did not show statistical significance

Statistically significant (p <0.05)