Table 2. List of C. glutamicum mutants with changes in the TCA cycle or in glutamate associated metabolites (GLU), or in both (bold).
ID | Position | Locus | Gene description | Operon | EC | Pearson | % OD | TCA | GLU |
P7A10 | 2361816 | NCgl2147 | Glutamate-ammonia-ligase adenylyltransferase | – | 2.7.7.42 | 0.97 | 67 | + | |
P7C5 | 2238004 | NCgl2038 | Hypothetical protein | – | – | 0.96 | 107 | + | |
P7C6 | Not identified | 0.92 | 50 | + | + | ||||
P7E1 | Not identified | 0.92 | 91 | + | |||||
P7F11 | 179131 | NCgl0163 | Major facilitator superfamily permease | + | – | 0.97 | 83 | + | + |
P8A2 | 368514 | NCgl0340 | Nucleoside-diphosphate sugar epimerase | + | – | 0.96 | 89 | + | |
P8D4 | Not identified | 0.93 | 42 | + | |||||
P8F4 | 1042752 | NCgl0944 | Major facilitator superfamily permease | – | – | 0.97 | 75 | + | |
P8F10 | 2380663 | NCgl2167 | Pyruvate dehydrogenase subunit E1 | – | 1.2.4.1 | 0.96 | 48 | + | + |
P8F12 | 1142652 | NCgl1051 | Hypothetical protein | + | – | 0.95 | 55 | + | + |
P8G3 | 1690962 | NCgl1533 | GTP cyclohydrolase II | + | 3.5.4.25 | 0.94 | 40 | + | + |
P21D2 | 3119587 | intergenic | – | – | 0.98 | 81 | + | ||
P21E9 | 1525622 | NCgl1392 | Hypothetical protein | + | – | 0.98 | 99 | + | |
P21G4 | 2867647 | NCgl2603 | Cell division protein | – | – | 0.98 | 87 | + | |
P21G11 | 199693 | NCgl0181 | Glutamate synthase large subunit | + | 1.4.1.13 | 0.98 | 119 | + |