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. 2014 Jan 25;5(1):3. doi: 10.1186/1878-5085-5-3

Table 1.

Criteria used to select breast cancer cases with deregulated PP2A in the cBioPortal for Cancer Genomics

Variable Criteria
Selects low expression (including deletions) of one of the pp2a complex components
 
  PPP2CA
Homozygous deletions; downregulation (fold change < −2)
  PPP2CB
  PPP2R2A
Selects high expression, including amplification, of the inhibitory regulatory subunits
 
  KIAA1524 (cip2a)
Amplification; upregulation (fold change >2)
  SETBP1
  SET
  IGBP1 (alpha4)