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. 2014 Feb 4;9(2):e87572. doi: 10.1371/journal.pone.0087572

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Results are shown as box plots of reactivity with each of the six V1V2-scaffold antigens with plasma from the 286 case-control specimens. Values are from ELISA-generated data with optical density (OD) read-outs based on a wavelength of 405 nM. Data were generated using plasma diluted 1∶100, except for assay of gp70.AE(92TH023)-V1V2 (1∶900) and tags.C(1086)-V1V2 (1∶300). Box plots show the 25^th percentile (lower edge of the box), 50^th percentile (horizontal line in the box), and 75^th percentile (upper edge of the box). Participants are stratified according to HIV-1 infection status and treatment assignment. Gender and immune response categories are indicated by the color and shape of the points. Low, Medium, and High are defined as tertiles of the Week 26 immune response for the vaccine group, and are divided by the gray shaded horizontal bands. AP and LL denote production of comparable reagents by Drs. Pinter and Liao.