. 2014 Feb 4;9(2):e87572. doi: 10.1371/journal.pone.0087572

Table 4. IgA-adjusted odds ratios of risk of HIV-1 infection (and p-values) based on data of Week 26 plasma reactivity with V1V2-scaffold antigens derived from two independent immunoassays.^* .

	ELISA^‡		BAMA^‡
	OR	p-value	OR	p-value
gp70.B(Case A2)-V1V2.AP_orig(primary)^{¥ §}	0.63	0.0179	ND	ND
gp70.B(Case A2.p623)-V1V2.AP_orig ^†	0.62	0.0149	0.60	0.0059
gp70.B(Case A2)-V1V2.LL^†	0.60	0.0084	0.59	0.0031
gp70.A(92RW020)-V1V2	0.68	0.0521	0.61	0.0071
gp70.C(97ZA012)-V1V2	0.56	0.0040	0.55	0.0008
tags.C(1086)-V1V2	0.53	0.0014	0.62	0.0039
gp70.AE(92TH023)-V1V2	0.62	0.0130	0.67	0.0097
Score (cross-reactivity)	0.58	0.0073	0.56	0.0015

Odds ratios are for every one standard deviation increase in the natural log-transformed OD (ELISA) or MFI (BAMA) and p-values for testing odds ratios equal to one are calculated using IgA-adjusted weighted logistic regression models as described in the text. The cross-reactivity score measures the average log10 response level across the four subtypes represented in the 6 V1V2 scaffolds, as defined in File S1.

^‡

ELISA = enzyme-linked immunosorbent assay; BAMA = binding antibody multiplex assay.

^¥

Data published in the original case-control study [3].

^†

AP and LL denote production of comparable reagents by Drs. Pinter and Liao.

^§

Reagent used in the original case-control study [3].

Table 4. IgA-adjusted odds ratios of risk of HIV-1 infection (and p-values) based on data of Week 26 plasma reactivity with V1V2-scaffold antigens derived from two independent immunoassays.* .

Table 4. IgA-adjusted odds ratios of risk of HIV-1 infection (and p-values) based on data of Week 26 plasma reactivity with V1V2-scaffold antigens derived from two independent immunoassays.^* .