Figure 1. Absence of spontaneous EAE in RR B10.S mice.

A. Incidence of spontaneous EAE in a cohort of RR SJL/J (n = 14) or RR B10.S mice (n = 17). B. Frequencies of CD3⁺ CD4⁺ T cells in spleen, pooled axillary and inguinal lymph nodes (pLN), mesenteric lymph nodes (mLN), Peyer's patches (PP) and small intestinal lamina propria (siLP) were measured by flow cytometry. C. Frequencies of Foxp3⁺ CD3⁺ CD4⁺ regulatory T cells in the indicated organs were measured by flow cytomtery. Results are from n  = 4–6 mice per group. Data were pooled from 2–3 different experiments (B–C). Error bars indicate SEM (B–C).