Table 1. Demographic characteristics and experimental composite scores across participant groupsa.
| Controls | bvFTD | AD | Group effect | bvFTD vs. Control | AD vs. Control | bvFTD vs. AD | |
| N | 35 | 22 | 32 | ||||
| Sex (M/F) | 19/16 | 14/8 | 20/12 | n.s. | . | . | . |
| Mean age (years) | 64.20 (5.38) | 61.23 (7.45) | 63.53 (6.98) | n.s. | . | . | . |
| Education (years) | 12.79 (2.60) | 11.33 (2.51) | 12.41 (3.28) | n.s. | . | . | . |
| Disease duration (years) | . | 3.82 (2.44) | 3.20 (2.09) | . | . | . | n.s. |
| FRS Rasch score b | . | −0.37 (1.02) | 0.25 (0.96) | . | . | . | n.s. |
| CDR sum of boxes [18] b | 0.32 (0.46) | 7.08 (2.86) | 5.05 (2.68) | *** | *** | *** | ** |
| ACE-R [100] | 95.00 (3.3) | 76.00 (10.47) | 67.84 (17.75) | *** | *** | *** | n.s. |
| CBI-R total frequency score [180] | 3.77 (4.57) | 67.36 (34.72) | 40.33 (26.48) | *** | *** | *** | n.s. |
| CBI-R selected subscores: | |||||||
| Memory/Orientation [32] | 1.50 (2.68) | 16.18 (6.95) | 16.00 (7.27) | *** | *** | *** | n.s. |
| Everyday skills [20] | 0.17 (0.389) | 7.09 (5.49) | 7.25 (5.599) | *** | *** | *** | n.s. |
| Abnormal behaviour [24] | 0.25 (0.45) | 9.18 (6.74) | 2.08 (2.31) | *** | *** | n.s. | ** |
| Stereotypic/motor behaviours [16] | 0.58 (0.79) | 7 (5.33) | 1.5 (2.15) | ** | *** | n.s. | ** |
| Recall composite | 99.56 (21.1) | 37.86 (28.76) | 20.55 (18.69) | *** | *** | *** | n.s. |
| DLPFC task composite | 99.53 (18.88) | 54.60 (26.03) | 57.39 (21.73) | *** | *** | *** | n.s. |
| VMPFC task composite | 99.81 (7.95) | 69.26 (17.19) | 82.88 (15.03) | *** | *** | *** | *** |
a
Standard deviations in parentheses, maximum score for tests shown in brackets.
b
All patients had either FRS or CDR disease severity measures.
**
p<.01, ***p<.001, n.s. = non-significant.