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. 2014 Feb 4;9(2):e87778. doi: 10.1371/journal.pone.0087778

Table 3. Voxel-based morphometry results showing regions of significant grey matter intensity decrease that covary with composite scores within the bvFTD group.

MNI Coordinates
Regions Hemisphere (L/R/B) X Y Z Numberof voxels T-score(peak voxel)
Recall
Parahippocampal gyrus/hippocampus L −24 −20 −34 1068 3.23
Parahippocampal gyrus/hippocampus R 22 −20 −32 813 3.23
Temporal pole L −48 18 −44 80 3.23
Paracingulate gyrus R 6 24 34 53 3.23
Frontal pole R 8 42 −28 48 3.23
Orbitofrontal cortex L −32 22 −26 38 3.23
Paracingulate gyrus R 18 50 4 31 3.23
Frontal pole R 42 60 6 29 3.23
Superior frontal gyrus L −22 8 72 27 3.23
Middle frontal gyrus R 32 30 22 24 3.23
Frontal pole/Orbitofrontal cortex L −28 36 −24 24 3.23
DLPFC tasks
Precentral gyrus/Supplementary cortex R 6 −14 58 502 3.23
Precentral gyrus/Postcentral gyrus L −48 −10 28 108 3.23
Middle frontal gyrus R 34 8 58 69 3.23
Precentral gyrus R 16 −28 40 43 2.93
Middle frontal gyrus L −34 14 62 33 2.93
Frontal pole/Middle frontal gyrus L −28 38 30 31 3.23
Precentral gyrus/Superior frontal gyrus L −20 −14 56 29 3.23
Precentral gyrus L −45 −10 32 28 2.52
Precentral gyrus/Middle frontal gyrus R 34 −6 52 27 3.23
Precentral gyrus L −57 4 38 25 2.75
Precentral gyrus R 62 6 32 23 2.52
Superior frontal gyrus R 12 4 72 22 2.75
Cingulate gyrus (posterior) L −14 −32 40 21 2.93
VMPFC tasks
Orbitofrontal cortex/Medial prefrontal cortex/Frontal pole B 12 24 −26 5589 3.23
Frontal pole R 8 46 46 96 3.23
Anterior cingulate gyrus R 10 24 28 86 2.93
Paracingulate gyrus B 2 32 44 69 3.23
Frontal pole R 24 46 38 62 2.75
Frontal pole L −52 42 12 57 3.23
Frontal pole L −38 44 36 46 3.23
Frontal pole/Superior frontal gyrus L −24 38 48 40 2.3
Frontal operculum cortex/Orbitofrontal cortex L −34 26 2 33 2.36
Anterior cingulate gyrus L −8 −14 38 28 2.93
Frontal pole L −12 52 44 25 2.52
Frontal pole L −26 38 28 24 2.3
Frontal pole L −18 64 26 22 2.3
Orbitofrontal cortex R 26 24 −26 21 2.1

Results FDR corrected at p<.05; only clusters with at least 20 contiguous voxels included.