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. 2014 Feb 4;9(2):e87778. doi: 10.1371/journal.pone.0087778

Table 4. Voxel-based morphometry results showing regions of significant grey matter intensity decrease that covary with composite scores within the AD group.

MNI Coordinates
Regions Hemisphere (L/R/B) X Y Z Numberof voxels T-score(peak voxel)
Recall
Precentral gyrus L −42 −14 46 559 3.11
Precentral gyrus/postcentral gyrus R 40 −24 58 182 3.11
Middle temporal gyrus (temporo-occipital part) R 66 −58 6 120 3.11
Supplementary motor cortex B 2 0 54 116 3.11
Middle temporal gyrus (posterior) R 70 −6 −26 108 3.11
Superior frontal gyrus R 22 −2 52 89 3.11
Temporal pole R 48 8 −52 69 3.11
Postcentral gyrus L −64 −20 38 52 3.11
Frontal pole L −10 76 12 44 3.11
Frontal pole R 60 42 −2 44 3.11
Middle frontal gyrus L −52 22 30 42 3.11
Frontal pole R 44 60 −18 35 3.11
Frontal pole L −16 62 38 33 3.11
Middle frontal gyrus R 32 24 26 33 3.11
Supramarginal gyrus/Middle temporal gyrus (temporo-occipital part) L −52 −50 12 32 3.11
DLPFC tasks
Precentral gyrus/Superior frontal gyrus L −24 −28 52 480 3.11
Middle frontal gyrus L −28 24 38 113 2.83
Precentral gyrus R 12 −16 72 27 2.55
Precentral gyrus R 22 −16 64 26 2.83
Superior frontal gyrus L −18 −6 56 26 2.67
Inferior frontal gyrus L −32 14 26 23 3.11
VMPFC tasks
Orbitofrontal cortex/Frontal pole L −24 22 −26 2130 3.11
Orbitofrontal cortex/Frontal pole R 24 20 −26 2101 3.11
Paracingulate gyrus/Cingulate gyrus B −12 50 18 621 3.11
Frontal pole R 12 62 22 124 3.11
Frontal pole R 38 56 10 63 3.11
Paracingulate gyrus R 12 48 −4 51 2.55
Frontal pole L −22 68 −2 47 2.67
Supplementary motor cortex R 10 2 46 41 2.83
Frontal pole L −4 70 2 31 2.67
Paracingulate gyrus R 12 16 44 26 2.67

Results FDR corrected at p<.05; only clusters with at least 20 contiguous voxels included.