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Molecular conditions leading to Zellweger-like syndromes in human and mouse. Biochemical and pathological consequences that are not common to all disorders are indicated. PEXn = any of the peroxisome biogenesis proteins that can be mutated in classical Zellweger syndrome. MFP1/2 = multifunctional proteins of peroxisomal beta-oxidation. DHAPAT = dihydroxyacetone phosphate acyl transferase. VLCFAs = very long-chain fatty acids. DHA = docosahexaenoic acid.
