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. 2014 Feb 4;9(2):e88256. doi: 10.1371/journal.pone.0088256

Figure 2. Accumulation and redistribution of repressive chromatin modifications during vole TS cell differentiation.

Figure 2

(A) uH2A forms distinct bands on Xi and is excluded from heterochromatic regions of Xi and other chromosomes. Immunostaining (uH2A, red and H3K9me3, green) combined with DNA FISH (MS4 repeat); (B) H3K27me3 accumulation on Xi. Immunostaining with antibodies to H3K27me3 (red) and HP1 (green) combined with DNA FISH (MS4 repeat). Metaphase spreads were counterstained with DAPI (blue). Active (Xa) and inactive (Xi) X-chromosomes are indicated by arrows.