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. 2013 Nov 25;99(2):448–454. doi: 10.1210/jc.2013-2942

Table 3.

Treatment Effect on Overall Survival by Risk Group (n = 2968)

n (%) Deceased n (%) Unadjusted HR (95% CI) P Value
Tumor size <2 cm and no distant metastases
    No surgery 17 (1.4) 1 (5.9) 1.00
    Lobectomy 139 (11.2) 18 (13.0) 2.35 (0.31, 17.64) .4050
    Total thyroidectomy 337 (27.0) 39 (11.6) 2.11 (0.29, 15.36) .4610
    Total thyroidectomy + regional lymph nodes resected 753 (60.4) 84 (11.2) 2.00 (0.28, 14.39) .4900
Tumor size >2.0 cm and no distant metastases
    No surgery 36 (2.6) 22 (61.1) 1.00
    Lobectomy 138 (9.9) 42 (30.4) 0.29 (0.18, 0.49) <.0001
    Total thyroidectomy 307 (22.0) 67 (21.8) 0.21 (0.13, 0.33) <.0001
    Total thyroidectomy + regional lymph nodes resected 912 (65.5) 252 (27.6) 0.26 (0.17, 0.40) <.0001
Any tumor size and distant metastases
    No surgery 148 (45.0) 126 (85.1) 1.00
    Lobectomy 25 (7.6) 19 (76.0) 0.63 (0.39, 1.02) .0590
    Total thyroidectomy 29 (8.8) 26 (89.7) 0.88 (0.58, 1.35) .5610
    Total thyroidectomy + regional lymph nodes resected 127 (38.6) 89 (70.1) 0.50 (0.38, 0.66) <.0001