Table 3.
Effect of 10-Week Soy Arm of Intervention on Serum Adipokine Concentrations (n = 60)a
| Biomarker | Geometric Mean (95% CI)b |
Ratio (95% CI) | PWeek 14 vs Week 24 | PChange Difference by BMI | |
|---|---|---|---|---|---|
| Week 14 | Week 24 | ||||
| Adiponectin, μg/mL | |||||
| All women | 14.38 (12.52–16.52) | 13.04 (11.21–15.17) | 0.91 (0.84–0.97) | .008 | .51 |
| BMI < 30 kg/m2 | 17.04 (14.31–20.29) | 15.18 (12.49–18.46) | 0.89 (0.81–0.98) | .01 | |
| BMI ≥ 30 kg/m2 | 11.42 (9.37–13.93) | 10.68 (8.57–13.30) | 0.93 (0.84–1.05) | .23 | |
| Leptin, ng/mL | |||||
| All women | 25.65 (20.89–31.48) | 23.63 (18.67–29.90) | 0.92 (0.80–1.07) | .27 | .06 |
| BMI < 30 kg/m2 | 18.32 (14.48–23.18) | 15.03 (11.65–19.38) | 0.82 (0.68–0.99) | .04 | |
| BMI ≥ 30 kg/m2 | 40.31 (30.51–53.27) | 43.81 (32.78–58.56) | 1.09 (0.86–1.37) | .47 | |
| A/L ratio | |||||
| All women | 0.56 (0.42–0.73) | 0.56 (0.41–0.75) | 1.00 (0.85–1.17) | >.99 | .18 |
| BMI < 30 kg/m2 | 0.92 (0.68–1.25) | 1.01 (0.73–1.40) | 1.09 (0.89–1.34) | .39 | |
| BMI ≥ 30 kg/m2 | 0.28 (0.20–0.40) | 0.25 (0.17–0.36) | 0.88 (0.68–1.13) | .31 | |
a
Ten women were excluded from these analyses due to insufficient serum samples for completion of adipokine measurements.
b
Adiponectin and leptin were not normally distributed and therefore were natural log transformed for normality; back-transformed data (geometric means and 95% CIs) are presented for ease of interpretation.