Fig. 9.

Micro-hamartomas in the brain of a 20-year-old man with NF-2. Low (a) and high (b) quality magnification of an area of the left thalamic deep gray matter in this patient with radiographic evidence of cortex dysplasia reveal dysplastic foci of glial cells without alterations of cytologic abnormalities or cortical architecture. Transverse fast fluid-attenuated inversion-recovery (FLAIR) sequences (c and d) demonstrate a cortical hyperintense lesion (arrows) suggestive of a cortical dysplasia in the left superior frontal gyrus in the same patient.