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Systemic sodium and ionized calcium loads during consecutive days of regional citrate anticoagulation (RCA)- and heparin anticoagulation (HA)-continuous renal replacement therapy (CRRT). Significant reduction of systemic sodium load on days 2, 3 and 4 versus the initial (pre-CRRT) value (day 0). p values were as follows: p 2 = 0.023; p 3 = 0.015; p 4 = 0.005
