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. 2013 Dec 4;7:101. doi: 10.3389/fnsys.2013.00101

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Copyright © 2013 Liu, Chang and Duyn.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Spontaneous activity at single fMRI time frames is suggestive of varying network involvement. Sample frames (T1-T13) from a representative fMRI scan show clear, distinct spatial patterns, some of which (red points) resemble the DMN pattern demonstrated by the PCC-based correlation map of this subject (right). The fMRI time course represents signal from the PCC seed region (green square). Small structures indicated by white arrows are the hippocampus (HI) and posterior parahippocampal gyrus (PHG) in T11 and the ventral lateral nucleus (VL) in T3. The color bar represents normalized BOLD signal for the sample frames and correlation values for the seed-based correlation map.