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. 2014 Jan 10;4(1):e170. doi: 10.1038/bcj.2013.68

Table 4. Overview of detected mutations in AML blasts and response outcome.

Gene Mutation Responders (CR/PR) (%)
KRAS G12D/V/A, G13D/A 3/6 (50)
NRAS G13D/V/A, Q61H 0/2 (0)
NPM1 W288C 0/4 (0)
IDH2 R140L/G 1/3 (33)
JAK2 V617F 2/2 (100)
MPL-2 W515L/X 0/2 (0)
DNMT3a R882C/H 0/2 (0)
FLT3 ITD 0/1 (0)