Table 1.
Strain | Background | Genotype | CamR Frequency | NalR Mutant Frequency |
TetR Mutant Frequency |
CarbR Frequency |
---|---|---|---|---|---|---|
AB1157 | K-12 | wild | <10−8 | 2 × 10−8 | <10−8 | <10−8 |
GM3819 | K-12 | Δdam-16 | <10−8 | 51 × 10−8 | <10−8 | <10−8 |
KM80 | EDL933 | wild | 1 – 10 × 10−8 | 3 × 10−8 | 2 × 10−8 | 1 – 4 × 10−8 |
KM69 | EDL933 | Δdam | 208 – 1500 × 10−8 | 152 × 10−8 | 105 × 10−8 | 2 – 12 × 10−8 |
GM9241 | EDL933 | marR | R | R | R | 24 – 558 × 10−8 |
Mutant frequency is expressed as the number of antibiotic resistant colonies per 108 cells. The numbers for Nal and Tet are the average of ten independent cultures. For Cam and Carb, the range of values from ten independent cultures are shown. R = resistant; Carb= carbenicillin, Nal = nalidixic acid, Tet = tetracycline