TABLE 1.
Baseline characteristics of patients with IAs*
| Characteristic | FIA Cohort | ISUIA Cohort |
p Value |
|---|---|---|---|
| no. of pts | 511 | 2419 | |
| mean age in yrs at study entry | 55.0 ± 11.5 | 55.4 ± 12.6 | 0.510 |
| no. of women (%) | 417 (81.6) | 1758 (72.7) | <0.001 |
| no. of white, non-Hispanic pts (%) | 438 (85.7) | 2222 (91.9) | <0.001 |
| unruptured IA frequency (%) | <0.001 | ||
| single | 329 (64.4) | 1743 (72.1) | |
| multiple | 182 (35.6) | 674 (27.9) | |
| total no. of unruptured IAs | 791 | 3380 | |
| location of largest IA (%) | 0.016 | ||
| ICA, cavernous ICA, OA | 194 (38.0) | 873 (36.1) | |
| ACoA, ACA | 75 (14.7) | 323 (13.4) | |
| MCA | 146 (28.6) | 603 (24.9) | |
| PCoA | 42 (8.2) | 332 (13.7) | |
| BA tip | 34 (6.7) | 173 (7.2) | |
| VBA (other than BA tip) | 20 (3.9) | 115 (4.8) | |
| no. w/ history of hypertension (%) | 252 (49.3) | 1022 (42.3) | 0.004 |
| cigarette smoking (%) | 0.001 | ||
| never smoked | 103 (20.2) | 598 (24.7) | |
| former smoker | 217 (42.5) | 814 (33.7) | |
| current smoker | 191 (37.4) | 997 (41.2) | |
| unknown | 0 (0.0) | 10 (0.4) | |
| alcoholic drinks, avg no./day (%) | <0.001 | ||
| never drinks | 320 (62.6) | 913 (37.7) | |
| <1 | 80 (15.7) | 943 (39.0) | |
| 1–2 | 81 (15.9) | 374 (15.5) | |
| 3–5 | 11 (2.2) | 121 (5.0) | |
| 6–8 | 5 (1.0) | 30 (1.2) | |
| ≥9 | 11 (2.2) | 18 (0.7) | |
| unknown | 3 (0.6) | 20 (0.8) | |
| caffeine drinks, avg no./day (%) | <0.001 | ||
| none | 30 (5.9) | 307 (12.7) | |
| <1 | 24 (4.7) | 544 (22.5) | |
| 1–2 | 137 (26.8) | 661 (27.3) | |
| 3–4 | 140 (27.4) | 598 (24.7) | |
| ≥5 | 179 (35.0) | 302 (12.5) | |
| unknown | 1 (0.2) | 7 (0.3) |
*
The mean age is expressed ± SD. Abbreviations: avg = average; pts = patients; VBA = vertebrobasilar artery.