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. Author manuscript; available in PMC: 2014 Feb 5.
Published in final edited form as: Pediatr Infect Dis J. 2012 Aug;31(8):842–847. doi: 10.1097/INF.0b013e31825c124a

TABLE 1.

Frequency of Outcomes of Interest from 6 to 36 Weeks of Age in CPT-Exposed and Unexposed Infants in Lilongwe, Malawi, During 2004–2009.

Outcome CPT-unexposed infants* (n = 283) CPT-exposed infants* (n = 1,239) Total (N = 1,522) P-value
Malaria (any severity) 70 (24.7%) 241 (19.5%) 311 (20.4%) 0.03
Anemia 49 (17.3%) 166 (13.4%) 215 (14.1%) 0.08
Severe illness or death 34 (12.0%) 135 (10.9%) 169 (11.1%) 0.59
 Diarrhea 11 (3.9%) 35 (2.8%) 46 (3.0%)
 Malaria(severe) 10 (3.5%) 14 (1.1%) 24 (1.6%)
 Meningitis 1 (0.4%) 9 (0.7%) 10 (0.7%)
 Pneumonia 5 (1.8%) 51 (4.1%) 56 (3.7%)
 Febrile illness 6 (2.1%) 22 (1.8%) 28 (1.8%)
 Vomiting 0 (0.0%) 2 (0.2%) 2 (0.1%)
 Death 1 (0.4%) 2 (0.2%) 3 (0.2%)
Low weight for age (Z score < -2) 46 (16.3%) 192 (15.6%) 238 (15.6%) 0.75
*

Infants were considered CPT-unexposed if > 36 weeks of age by June 13, 2006; infants were considered CPT-exposed if they reached 6 weeks of age on or after August 15, 2006.

P-value based on chi-square test comparing CPT-exposed and CPT-unexposed groups. CPT = cotrimoxazole preventive therapy